Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.46 |
| ▸ | CSF1R | P07333 | 13/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KIF5B | P33176 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909222 | 0.74 | CSF1R (0.58) | EGFRCSF1RPDGFRBPDGFRARET | |
| SCHEMBL7466353 | 0.74 | EGFR (0.47) | EGFRCSF1RPDGFRBPDGFRA | |
| SCHEMBL27451555 | 0.67 | PKM (0.38) | EGFRCSF1RPDGFRBPDGFRA | |
| SCHEMBL8900055 | 0.66 | EGFR (0.69) | EGFRCSF1R | |
| SCHEMBL8897798 | 0.66 | MAP4K4 (0.58) | EGFRCSF1R | |
| Hydrochloric Acid SCHEMBL6039704 | 0.65 | EGFR (0.67) | EGFRCSF1RPDGFRBPDGFRA | |
| SCHEMBL23576765 | 0.63 | EGFR (0.43) | EGFRCSF1RPDGFRBKDR | |
| SCHEMBL8177845 | 0.63 | EGFR (1.00) | EGFRCSF1RPDGFRBPDGFRARET | |
| SCHEMBL2257706 | 0.63 | CSF1R (1.00) | EGFRCSF1RPDGFRBPDGFRARET | |
| SCHEMBL30014070 | 0.63 | EGFR (0.54) | EGFRCSF1RPDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |