Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | EEF2K | O00418 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469793 | 0.83 | DRD4 (0.57) | KMT2ADRD4SIGMAR1HTR7 | |
| SCHEMBL7468042 | 0.81 | SIGMAR1 (0.58) | MEN1KMT2ASIGMAR1HTR7 | |
| SCHEMBL9203755 | 0.76 | KDM4E (0.64) | EEF2K | |
| SCHEMBL12943597 | 0.75 | GRIN2B (0.45) | DRD4SIGMAR1HTR7 | |
| SCHEMBL4527775 | 0.75 | DRD4 (0.57) | KMT2ADRD4SIGMAR1HTR7 | |
| SCHEMBL932530 | 0.74 | GRIN2B (0.44) | SIGMAR1HTR7 | |
| SCHEMBL4889612 | 0.74 | DRD4 (0.54) | KMT2AMAPK1DRD4SIGMAR1 | |
| SCHEMBL27811558 | 0.73 | CYP2D6 (0.51) | MEN1KMT2AMAPK1SIGMAR1 | |
| SCHEMBL13020353 | 0.73 | NCF1 (0.45) | MEN1KMT2AMAPK1 | |
| SCHEMBL8725812 | 0.73 | SIGMAR1 (0.75) | MEN1KMT2ASIGMAR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |