Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551194 | 0.78 | PPARG (0.58) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL7474373 | 0.75 | PPARD (0.65) | MRGPRX4MAOBPPARAPPARD | |
| SCHEMBL18440586 | 0.73 | SRD5A2 (0.55) | SRD5A2MRGPRX4KDM4C | |
| SCHEMBL7554575 | 0.72 | PPARA (0.44) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL15141030 | 0.72 | SRD5A2 (0.68) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL8187385 | 0.72 | MAOA (0.59) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL4424324 | 0.72 | MAOB (0.59) | MRGPRX4MAOBPPARAMAOAPPARG | |
| SCHEMBL7814884 | 0.71 | PTGER3 (0.57) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL7814883 | 0.71 | PTGER3 (0.57) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL8158239 | 0.71 | FFAR1 (0.58) | MAOBPPARAMAOAPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252178-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-10-30 | — | — | EP | claimed |
| WO-2001040262-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-06-07 | — | — | WO | claimed |