Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551194 | 0.84 | PPARG (0.58) | PPARAPPARGMAOBKDM4EALDH1A1 | |
| SCHEMBL7474368 | 0.72 | KDM4E (0.52) | PPARAPPARGPPARDMAOBKDM4E | |
| SCHEMBL14571496 | 0.70 | PPARA (0.61) | PPARAPPARGPPARDMAOBFFAR1 | |
| SCHEMBL853406 | 0.69 | KDM4E (0.58) | PPARAPPARGPPARDMAOBKDM4E | |
| SCHEMBL853304 | 0.69 | KDM4E (0.58) | PPARAPPARGPPARDMAOBKDM4E | |
| SCHEMBL8158239 | 0.69 | FFAR1 (0.58) | PPARAPPARGMAOBFFAR1S1PR1 | |
| SCHEMBL31722407 | 0.69 | MAOB (0.57) | MAOBKDM4EHPGD | |
| SCHEMBL5382586 | 0.67 | PPARA (0.63) | PPARAPPARGPPARDMAOB | |
| SCHEMBL30375840 | 0.67 | MAOB (0.52) | PPARAPPARDMAOB | |
| SCHEMBL5377069 | 0.66 | PPARA (0.69) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032330-A1 | Propionic acid derivatives | NOMURA YUTAKA (JP) | 2002-03-14 | — | — | US | disclosed |
| EP-0994095-A1 | PROPIONIC ACID DERIVATIVES | NIPPON CHEMIPHAR CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032330-A1 | Propionic acid derivatives | ABAT, ACAT1, PDXK | PPARA 56/4885PPARG 123/4885PPARD 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.