Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623869 | 0.79 | FFAR1 (0.58) | FFAR1PPARGPPARAMAOBPTPN1 | |
| SCHEMBL3969699 | 0.78 | FFAR1 (0.60) | FFAR1PPARGPPARAMAOBPTPN1 | |
| SCHEMBL31722407 | 0.73 | MAOB (0.57) | MAOBMAOA | |
| SCHEMBL21504828 | 0.73 | FFAR1 (0.68) | FFAR1PPARGPPARA | |
| SCHEMBL4857396 | 0.73 | PPARG (0.56) | FFAR1PPARGPPARA | |
| SCHEMBL8312136 | 0.72 | FFAR1 (0.87) | FFAR1PPARGPPARA | |
| SCHEMBL7474368 | 0.71 | KDM4E (0.52) | FFAR1PPARGPPARAMAOBMAOA | |
| SCHEMBL14281406 | 0.71 | FFAR1 (0.67) | FFAR1PPARGPPARA | |
| SCHEMBL7551194 | 0.70 | PPARG (0.58) | PPARGPPARAMAOBPTPN1MAOA | |
| SCHEMBL8932685 | 0.70 | HDAC8 (0.53) | FFAR1PPARGPPARAMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121288-A | DECREASING VISCERAL FAT, INHIBITING ACCUMULATION OF VISCERAL FAT AND IMPROVING THE DISTRIBUTION OF VISCERAL FAT BY ADMINISTERING A 5-SUBSTITUTED-2,4-THIAZOLIDINEDIONE DERIVATIVE OF GIVEN FORMULA | NIPPON CHEMIPHAR CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |