Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GRK2 | P25098 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765662 | 0.96 | RAB9A (0.41) | CA1CA2CA9RAB9ANPC1 | |
| SCHEMBL8691883 | 0.82 | STING1 (0.42) | POLBPKMSMN1; SMN2TDP1MEN1 | |
| SCHEMBL30938481 | 0.79 | RAB9A (0.59) | RAB9ANPC1POLBPKMSMN1; SMN2 | |
| SCHEMBL6036198 | 0.79 | RAB9A (0.59) | RAB9ANPC1POLBPKMSMN1; SMN2 | |
| SCHEMBL2190433 | 0.79 | POLB (0.59) | POLBPKMGRK2SMN1; SMN2CTDSP1 | |
| SCHEMBL28135499 | 0.77 | MAPK1 (0.50) | RAB9APOLBPKMSMN1; SMN2KMT2A | |
| SCHEMBL24499421 | 0.77 | NPC1 (0.59) | CA1CA2CA12CA9RAB9A | |
| SCHEMBL22279550 | 0.76 | CA1 (0.59) | CA1CA2CA12CA9RAB9A | |
| SCHEMBL21765907 | 0.75 | TSHR (0.51) | RAB9APOLBPKMSMN1; SMN2MEN1 | |
| SCHEMBL1431346 | 0.74 | NPC1 (0.62) | RAB9ANPC1POLBPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |