Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13018932 | 0.83 | SMN1; SMN2 (0.59) | TSHRPOLBMAPTHTTKDM4E | |
| SCHEMBL5226832 | 0.83 | PKM (0.60) | POLBMAPTHTTKMT2AALDH1A1 | |
| SCHEMBL30381367 | 0.83 | PKM (0.60) | POLBMAPTHTTKMT2AALDH1A1 | |
| SCHEMBL23417746 | 0.81 | TSHR (0.51) | TSHRPOLBMAPTHTTKDM4E | |
| SCHEMBL5186769 | 0.81 | RAB9A (0.62) | TSHRMAPTHTTKDM4EKMT2A | |
| SCHEMBL8773849 | 0.81 | MEN1 (0.67) | TSHRPOLBHTTKDM4EKMT2A | |
| SCHEMBL28135499 | 0.80 | MAPK1 (0.50) | POLBHTTKDM4EKMT2AALDH1A1 | |
| SCHEMBL19464682 | 0.80 | ALDH1A1 (0.60) | TSHRPOLBMAPTKDM4EKMT2A | |
| SCHEMBL21247043 | 0.79 | ADORA3 (0.43) | TSHRPOLBMAPTHTTKDM4E | |
| SCHEMBL21765662 | 0.78 | RAB9A (0.41) | POLBMAPTKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |