Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460778 | 0.89 | ACHE (0.51) | ACHEBACE1PDE10APDGFRBHTR2A | |
| SCHEMBL7462862 | 0.85 | PDGFRB (0.44) | ACHEBACE1PDE10APDGFRBHTR2A | |
| SCHEMBL7469954 | 0.83 | PDGFRB (0.44) | ACHEBACE1PDGFRBHTR2AHTR2C | |
| SCHEMBL7476089 | 0.83 | PDGFRB (0.41) | ACHEBACE1PDE10APDGFRBCYP1A2 | |
| SCHEMBL7465618 | 0.82 | PDGFRB (0.42) | ACHEBACE1PDE10APDGFRBHTR2A | |
| SCHEMBL7465661 | 0.73 | ACHE (0.45) | ACHEBACE1PDE10APDGFRBUSP2 | |
| SCHEMBL7473072 | 0.72 | MAPT (0.39) | ACHEBACE1PDGFRBALDH1A1CYP1A2 | |
| SCHEMBL8500247 | 0.72 | PDE10A (0.50) | ACHEBACE1PDE10APDGFRBALDH1A1 | |
| SCHEMBL7465361 | 0.71 | MAPT (0.43) | ACHEBACE1USP2ALDH1A1CYP1A2 | |
| SCHEMBL7470741 | 0.71 | MAPT (0.42) | ACHEBACE1PDE10AUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |