SCHEMBL7474674

SCHEMBL7474674

CCCCCCCCCCCCCCCCCCOC(=O)N1CCCCC1CCNCCCN(C)C

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GBA2 Q9HCG7 1/20 0.38
DPP4 P27487 3/20 0.36
EPHX2 P34913 1/20 0.36
DNM1 Q05193 2/20 0.36
PAOX Q6QHF9 1/20 0.34
FKBP1A P62942 2/20 0.34
MAPT P10636 1/20 0.34
F2 P00734 1/20 0.34
PRSS1 P07477 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7478291 0.96 DPP4 (0.38) GBA2DPP4EPHX2PAOXMAPT
SCHEMBL7470814 0.87 ACHE (0.44) EPHX2DNM1
Hydrochloric Acid SCHEMBL7477849 0.86 ACHE (0.43) EPHX2DNM1
SCHEMBL7479285 0.86 GBA2 (0.40) GBA2DNM1FKBP1AMAPTF2
SCHEMBL7482175 0.86 GBA2 (0.40) GBA2DNM1FKBP1AMAPTF2
SCHEMBL7472878 0.84 GBA2 (0.38) GBA2EPHX2DNM1MAPT
SCHEMBL7480020 0.84 MEN1 (0.47) DPP4DNM1PAOXMAPT
SCHEMBL7479038 0.83 ACHE (0.41) EPHX2
SCHEMBL7475380 0.82 GBA2 (0.48) GBA2EPHX2FKBP1AMAPT
SCHEMBL7471137 0.82 MEN1 (0.45) DPP4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933361-B1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO CO LTD (JP) 2002-03-27 EP disclosed
US-6057337-A USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS SHISEIDO CO., LTD. (JP) 2000-05-02 US disclosed
EP-0933361-A1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO COMPANY LIMITED (JP) 1999-08-04 EP disclosed