Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479285 | 0.98 | GBA2 (0.40) | GBA2DNM1MAPTF2PRSS1 | |
| SCHEMBL7474984 | 0.88 | DNM1 (0.50) | GBA2DNM1MAPTPRSS1NAAA | |
| SCHEMBL7472878 | 0.87 | GBA2 (0.38) | GBA2DNM1MAPTNAAAS1PR1 | |
| SCHEMBL7483710 | 0.86 | GBA2 (0.41) | GBA2MAPTF2PRSS1S1PR1 | |
| SCHEMBL7478386 | 0.86 | GBA2 (0.41) | GBA2MAPTF2PRSS1S1PR1 | |
| SCHEMBL7478291 | 0.86 | DPP4 (0.38) | GBA2MAPT | |
| SCHEMBL7474674 | 0.86 | GBA2 (0.38) | GBA2DNM1MAPTF2PRSS1 | |
| SCHEMBL7479038 | 0.86 | ACHE (0.41) | — | |
| SCHEMBL7470814 | 0.86 | ACHE (0.44) | DNM1 | |
| SCHEMBL7479855 | 0.85 | NPC1 (0.44) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |