SCHEMBL7478291

SCHEMBL7478291

CCCCCCCCCCCCCCCCCCNCCC1CCCCN1C(=O)OCCCN(C)C

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.38
GBA2 Q9HCG7 1/20 0.35
EPHX1 P07099 8/20 0.34
EPHX2 P34913 2/20 0.34
PAOX Q6QHF9 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7474674 0.96 GBA2 (0.38) DPP4GBA2EPHX2PAOXMAPT
SCHEMBL7479038 0.87 ACHE (0.41) EPHX1EPHX2
SCHEMBL7482175 0.86 GBA2 (0.40) GBA2MAPT
SCHEMBL7479285 0.84 GBA2 (0.40) GBA2MAPT
SCHEMBL7471137 0.84 MEN1 (0.45) DPP4MAPT
SCHEMBL7474984 0.83 DNM1 (0.50) GBA2EPHX2MAPT
SCHEMBL8198867 0.83 DPP4 (0.39) DPP4PAOXMAPT
SCHEMBL7470814 0.83 ACHE (0.44) EPHX2
SCHEMBL7472878 0.82 GBA2 (0.38) GBA2EPHX2MAPT
Hydrochloric Acid SCHEMBL7477849 0.82 ACHE (0.43) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933361-B1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO CO LTD (JP) 2002-03-27 EP disclosed
US-6057337-A USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS SHISEIDO CO., LTD. (JP) 2000-05-02 US disclosed
EP-0933361-A1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO COMPANY LIMITED (JP) 1999-08-04 EP disclosed