Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479206 | 0.87 | HRH3 (0.44) | HRH4HRH3ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL15555557 | 0.76 | ALDH1A1 (0.49) | HRH4HRH3ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL20470604 | 0.75 | ALDH1A1 (0.51) | HRH4HRH3ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL6962088 | 0.73 | HRH4 (0.43) | HRH4HRH3ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL14974505 | 0.72 | HRH4 (0.44) | HRH4HRH3L3MBTL1TDP1HCAR2 | |
| SCHEMBL6703361 | 0.70 | PARP1 (0.43) | TSHRTP53POLB | |
| SCHEMBL1001167 | 0.70 | TSHR (0.58) | HRH4HRH3ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL8186168 | 0.69 | L3MBTL1 (0.50) | HRH4HRH3ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL8998380 | 0.69 | TSHR (0.56) | HRH4HRH3ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL3488296 | 0.69 | TSHR (0.56) | HRH4HRH3L3MBTL1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-A4 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2002-10-30 | — | — | EP | disclosed |
| EP-1169320-A1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG Chem Investment, Ltd. (KR) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000064891-A1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2000-11-02 | — | — | WO | disclosed |