Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 12/20 | 0.40 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479941 | 0.93 | PPARD (0.43) | ICMTPPARDPPARGPPARAPLA2G2A | |
| SCHEMBL6598709 | 0.88 | THRA (0.44) | ICMTPPARDPPARGPPARAPLA2G2A | |
| SCHEMBL6599665 | 0.86 | PLA2G2A (0.39) | ICMTPPARDPPARGPPARAPLA2G2A | |
| SCHEMBL6598794 | 0.86 | PLA2G2A (0.47) | ICMTPPARDPPARGPPARAPLA2G2A | |
| SCHEMBL6601718 | 0.86 | PLA2G2A (0.38) | ICMTPPARDPPARGPPARAPLA2G2A | |
| SCHEMBL5810585 | 0.85 | PLA2G2A (0.41) | ICMTPPARDPPARGPPARAPLA2G2A | |
| Acetic Acid SCHEMBL6598580 | 0.85 | S1PR1 (0.40) | ICMTPPARDPPARGPPARAPLA2G2A | |
| SCHEMBL5810419 | 0.84 | PPARD (0.53) | ICMTPPARDPPARGPPARAPLA2G2A | |
| SCHEMBL6597512 | 0.84 | PLA2G2A (0.37) | ICMTPPARDPPARGPPARAPLA2G2A | |
| SCHEMBL6603373 | 0.84 | PPARD (0.44) | ICMTPPARDPPARGPPARAPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| EP-0880519-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997027190-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-31 | — | — | WO | disclosed |