Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.43 |
| ▸ | PPARA | Q07869 | 8/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | ICMT | O60725 | 7/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474848 | 0.93 | ICMT (0.40) | PPARDPPARAPPARGICMTPLA2G2A | |
| SCHEMBL5810419 | 0.91 | PPARD (0.53) | PPARDPPARAPPARGICMTLTB4R | |
| SCHEMBL8624729 | 0.89 | THRA (0.46) | PPARDPPARAPPARGICMTLTB4R | |
| SCHEMBL6598614 | 0.87 | PPARD (0.48) | PPARDPPARAPPARGICMTLTB4R | |
| SCHEMBL6601187 | 0.87 | PLA2G2A (0.49) | PPARDPPARAPPARGICMTPLA2G2A | |
| SCHEMBL5809194 | 0.86 | THRA (0.41) | PPARDPPARAPPARGICMTLTB4R | |
| SCHEMBL6599833 | 0.86 | PLA2G2A (0.47) | PPARDPPARAPPARGICMTPLA2G2A | |
| Acetic Acid SCHEMBL6610409 | 0.85 | S1PR1 (0.42) | PPARDPPARAPPARGICMTPLA2G2A | |
| SCHEMBL6599124 | 0.85 | PLA2G2A (0.42) | PPARDPPARAPPARGICMTPLA2G2A | |
| Hydrochloric Acid SCHEMBL8470607 | 0.84 | PLA2G2A (0.42) | PPARDPPARAPPARGICMTPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |