Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1416018 | 0.82 | POLB (0.33) | MEN1KMT2AHSD17B10LMNAL3MBTL1 | |
| SCHEMBL751033 | 0.81 | RAB9A (0.48) | KMT2ALMNATSHRNPC1RAB9A | |
| SCHEMBL8749753 | 0.78 | RAB9A (0.54) | TSHRNPC1MAPTRAB9ATSPO | |
| SCHEMBL10811798 | 0.77 | ATM (0.35) | LMNAL3MBTL1TSHR | |
| SCHEMBL2291003 | 0.77 | ELANE (0.45) | MEN1KMT2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL1416078 | 0.76 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL3120409 | 0.75 | LMNA (0.44) | HSD17B10LMNATSHRSMN1; SMN2NPC1 | |
| SCHEMBL3123209 | 0.75 | SMN1; SMN2 (0.38) | MEN1KMT2ALMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL3120403 | 0.75 | ALDH1A1 (0.43) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL5731394 | 0.75 | TSHR (0.43) | MEN1KMT2AHSD17B10L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | claimed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | claimed |
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |