Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469891 | 0.88 | HTR2A (0.48) | ALDH1A1PKMMEN1KMT2AL3MBTL1 | |
| SCHEMBL7465150 | 0.87 | PKM (0.56) | ALDH1A1PKMSMN1; SMN2L3MBTL1GAA | |
| SCHEMBL13152700 | 0.80 | ALDH1A1 (0.60) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| SCHEMBL7468301 | 0.80 | CXCR4 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13888771 | 0.72 | ALDH1A1 (0.63) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| SCHEMBL13922018 | 0.71 | ALDH1A1 (0.58) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| SCHEMBL17069876 | 0.70 | POLB (0.57) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| SCHEMBL8217502 | 0.69 | ALDH1A1 (0.62) | ALDH1A1PKMHDAC3HDAC4HDAC1 | |
| SCHEMBL12101129 | 0.69 | PKM (0.75) | ALDH1A1PKMMEN1KMT2AHPGD | |
| SCHEMBL8885165 | 0.69 | ALDH1A1 (0.63) | ALDH1A1PKMHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |