Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | ESRRB | O95718 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESRRA | P11474 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663363 | 0.79 | MAPT (0.51) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL24670765 | 0.79 | KMT2A (0.60) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL7580016 | 0.76 | USP2 (0.45) | SMN1; SMN2MEN1KMT2ACYP2C19NPSR1 | |
| SCHEMBL8462423 | 0.75 | MAPT (0.47) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL8662409 | 0.75 | MAPT (0.54) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL29803554 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL24670882 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL7350120 | 0.73 | MAPT (0.51) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL8660500 | 0.73 | KIT (0.49) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL5081454 | 0.72 | NAMPT (0.65) | SMN1; SMN2MEN1KMT2ACYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885205-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-0885205-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997031910-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-09-04 | — | — | WO | disclosed |