Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429161 | 0.85 | MAPT (0.53) | USP2ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL24670708 | 0.79 | MEN1 (0.55) | USP2ALDH1A1TSHRHSD17B10HTR2A | |
| SCHEMBL7477992 | 0.78 | RAB9A (0.55) | USP2ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL7475144 | 0.76 | SMN1; SMN2 (0.46) | USP2ALDH1A1TSHRMAPTCYP2C19 | |
| SCHEMBL7584355 | 0.76 | MAPT (0.54) | ALDH1A1HSD17B10MAPTITGB3ITGA2B | |
| SCHEMBL8321062 | 0.75 | KIT (0.48) | USP2ALDH1A1HSD17B10HTR2AHTR2C | |
| Trifluoroacetic Acid SCHEMBL29803818 | 0.74 | SLC2A1 (0.52) | USP2ALDH1A1TSHRHSD17B10HTR2A | |
| SCHEMBL7445054 | 0.71 | MCHR1 (0.49) | USP2ALDH1A1TSHRHSD17B10HTR2A | |
| SCHEMBL7351038 | 0.71 | MCHR1 (0.52) | USP2ALDH1A1TSHRHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL7437697 | 0.71 | MCHR1 (0.48) | USP2ALDH1A1TSHRHSD17B10HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885205-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-0885205-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997031910-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-09-04 | — | — | WO | disclosed |