Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.44 |
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5842061 | 1.00 | CTSS (0.44) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL5841164 | 0.86 | ADORA1 (0.49) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL5837074 | 0.86 | ADORA1 (0.49) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL5838097 | 0.83 | CTSS (0.45) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL6230968 | 0.71 | GPR119 (0.37) | — | |
| SCHEMBL21010315 | 0.66 | CTSS (0.79) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL10040933 | 0.66 | CTSS (0.79) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL2440946 | 0.66 | CTSS (0.79) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL12204485 | 0.66 | CTSS (0.77) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL3383006 | 0.66 | CTSS (0.77) | CTSSCTSKCTSBCTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214325-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001019831-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2001-03-22 | — | — | WO | disclosed |