SCHEMBL7475382

SCHEMBL7475382

CCCCCCCCCCCCNC1CC(C)(C)N(OCc2ccccc2C)C(C)(C)C1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.38
CHRM2 P08172 2/20 0.36
ESR1 P03372 1/20 0.35
CNR1 P21554 2/20 0.33
CNR2 P34972 1/20 0.33
GNAI3 P08754 2/20 0.33
GNAO1 P09471 2/20 0.33
GNAI1 P63096 2/20 0.33
EPHX2 P34913 1/20 0.32
S1PR4 O95977 1/20 0.32
S1PR1 P21453 1/20 0.32
S1PR3 Q99500 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7476946 0.95 SLC2A1 (0.35) SLC2A1CHRM2EPHX2
SCHEMBL9039574 0.76 KMT2A (0.41) EPHX2S1PR1
SCHEMBL9491106 0.76 GNAI3 (0.41) SLC2A1CNR1CNR2GNAI3GNAO1
SCHEMBL26668878 0.76 GNAI3 (0.41) SLC2A1CNR1CNR2GNAI3GNAO1
SCHEMBL8532351 0.76 GNAI3 (0.41) SLC2A1CNR1CNR2GNAI3GNAO1
SCHEMBL7475386 0.74 SLC2A1 (0.38) SLC2A1CNR1CNR2GNAI3GNAO1
SCHEMBL10160218 0.74 GNAI3 (0.42) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL9656558 0.74 KMT2A (0.44) ESR1EPHX2S1PR1
SCHEMBL9354117 0.73
SCHEMBL870983 0.73 GNAI3 (0.38) SLC2A1CNR1CNR2GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0309402-B2 N-substituted hindered amine stabilizers CIBA SC HOLDING AG (CH) 2002-06-12 EP disclosed
EP-0309402-B1 N-substituted hindered amine stabilizers CIBA GEIGY AG (CH) 1995-01-11 EP disclosed
EP-0389430-B1 N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties CIBA GEIGY AG (CH) 1994-10-26 EP disclosed
US-5204473-A O-substituted N-hydroxy hindered amine stabilizers CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
US-5021481-A For use with polymers CIBA-GEIGY CORPORATION (US) 1991-06-04 US disclosed
EP-0389430-A1 N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed
EP-0309402-A1 N-substituted hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed