Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.44 |
| ▸ | PTPRC | P08575 | 3/20 | 0.42 |
| ▸ | PTPRF | P10586 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480004 | 0.85 | MEN1 (0.43) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| SCHEMBL7487467 | 0.80 | PTPN1 (0.67) | PTPN1PTPRCPTPRFCDC25BCES1 | |
| SCHEMBL1409136 | 0.80 | KMT2A (0.38) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| SCHEMBL1409137 | 0.80 | KMT2A (0.38) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| SCHEMBL7474177 | 0.75 | PTPN1 (0.42) | PTPN1PTPRCPTPRFCDC25BRAB9A | |
| SCHEMBL30424078 | 0.71 | BACE1 (0.43) | PTPN1CDC25BMEN1RAB9AKMT2A | |
| SCHEMBL8401213 | 0.70 | CDC25A (0.44) | PTPN1PTPRCCDC25BMEN1RAB9A | |
| SCHEMBL19698857 | 0.66 | ALDH1A1 (0.58) | MEN1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL4192820 | 0.65 | PTPN1 (0.61) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| SCHEMBL11411223 | 0.65 | MEN1 (0.58) | MEN1RAB9AKMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025107-B1 | PHOTOCHROMIC COMPOUNDS | JAMES ROBINSON LTD (GB) | 2002-08-07 | — | — | EP | claimed |
| US-6303673-B1 | FOR OPTICAL ELEMENTS | JAMES ROBINSON LIMITED (GB) | 2001-10-16 | — | — | US | claimed |
| EP-1025107-B1 | PHOTOCHROMIC COMPOUNDS | JAMES ROBINSON LTD (GB) | 2002-08-07 | — | — | EP | disclosed |
| US-6303673-B1 | FOR OPTICAL ELEMENTS | JAMES ROBINSON LIMITED (GB) | 2001-10-16 | — | — | US | disclosed |