SCHEMBL1409136

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1409137	1.00	KMT2A (0.38)	KMT2AMEN1PABPC1PTPN1RAB9A
	SCHEMBL7480004	0.92	MEN1 (0.43)	KMT2AMEN1PTPN1RAB9ANPC1
	SCHEMBL1409019	0.85	PTPN1 (0.54)	KMT2AMEN1PABPC1PTPN1RAB9A
	SCHEMBL7475394	0.80	PTPN1 (0.44)	KMT2AMEN1PTPN1RAB9AGAA
	SCHEMBL27833505	0.76	KMT2A (0.33)	KMT2AMEN1RAB9ANPC1GAA
	SCHEMBL4192820	0.74	PTPN1 (0.61)	KMT2AMEN1PTPN1RAB9ANPC1
	SCHEMBL6688709	0.69	BACE1 (0.60)	KMT2AMEN1PTPN1RAB9ANPC1
	SCHEMBL7153625	0.69	ALDH1A1 (0.48)	KMT2AMEN1RAB9ANPC1GAA
	SCHEMBL8038944	0.68	ALDH1A1 (0.50)	KMT2AMEN1RAB9ANPC1GAA
	SCHEMBL4176541	0.68	PTPN1 (0.55)	PTPN1ALDH1A1PTPRCPTPRFCDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.