Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.50 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478300 | 0.91 | GABRA1 (0.52) | LTA4HPLA2G2AKDM4EHPGDMAPT | |
| SCHEMBL7476207 | 0.84 | GABRA1 (0.58) | KDM4EHPGDMAPTHSD17B10LMNA | |
| SCHEMBL7480676 | 0.81 | CYSLTR1 (0.51) | KDM4EMAPTHSD17B10LMNAALDH1A1 | |
| SCHEMBL5504619 | 0.75 | KDM4E (0.69) | KDM4EHPGDMAPTHSD17B10LMNA | |
| SCHEMBL25904016 | 0.75 | TRPM8 (0.59) | KDM4EHPGDMAPTHSD17B10LMNA | |
| SCHEMBL6600768 | 0.73 | TRPM8 (0.57) | KDM4EHPGDMAPTHSD17B10LMNA | |
| SCHEMBL28819188 | 0.73 | GABRA1 (0.59) | KDM4EHPGDMAPTHSD17B10LMNA | |
| SCHEMBL22074470 | 0.72 | TRPM8 (0.54) | LTA4HPLA2G2AKDM4EHPGDMAPT | |
| SCHEMBL4151637 | 0.71 | TRPM8 (0.57) | KDM4EHPGDMAPTHSD17B10LMNA | |
| Pivalate SCHEMBL27561429 | 0.71 | KDM4E (0.54) | LTA4HPLA2G2AKDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |