Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.38 |
| ▸ | MTOR | P42345 | 4/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28183997 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KMT2ALMNAPOLB | |
| SCHEMBL27624144 | 0.71 | MAPK1 (0.35) | ALDH1A1HSD17B10HPGDPIK3CAMTOR | |
| SCHEMBL14553277 | 0.69 | ALDH1A1 (0.51) | ALDH1A1KMT2ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL7479786 | 0.69 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDPIK3CAMTOR | |
| SCHEMBL5650037 | 0.68 | CYP1A2 (0.47) | ALDH1A1HSD17B10HPGDRECQLNPSR1 | |
| SCHEMBL10904452 | 0.68 | ALDH1A1 (0.53) | ALDH1A1HSD17B10HPGDPIK3CAMTOR | |
| SCHEMBL27949532 | 0.67 | CYP2A13 (0.37) | ALDH1A1HSD17B10HPGDMAPTGAA | |
| SCHEMBL18322749 | 0.64 | HCAR1 (0.38) | ALDH1A1HSD17B10HPGDPIK3CAMTOR | |
| SCHEMBL28853334 | 0.63 | ALDH1A1 (0.35) | ALDH1A1KMT2APOLB | |
| SCHEMBL5924019 | 0.61 | ALDH1A1 (0.37) | ALDH1A1HSD17B10MAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020061919-A1 | PROCESS FOR THE PREPARATION OF 1,2,3,9-TETRAHYDRO-9-METHYL-3-{(2-METHYL-1H-IMIDAZOL-1-YL)METHYL}-4H-CARBAZOL-4-ONE | HANMI PHARM. CO., LTD. (KR) | 2002-05-23 | — | — | US | claimed |
| EP-1207160-A1 | Process for the preparation of 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)-methyl)-4H-carbazol-4-one | Hanmi Pharm. Co., Ltd. (KR) | 2002-05-22 | — | — | EP | claimed |
| US-6388091-B1 | IN PRESENCE OF A HALOSILANE COMPOUND; CRYSTALLIZATION, PURIFICATION | HANMI PHARM. CO., LTD. (KR) | 2002-05-14 | — | — | US | claimed |
| US-20020061919-A1 | PROCESS FOR THE PREPARATION OF 1,2,3,9-TETRAHYDRO-9-METHYL-3-{(2-METHYL-1H-IMIDAZOL-1-YL)METHYL}-4H-CARBAZOL-4-ONE | HANMI PHARM. CO., LTD. (KR) | 2002-05-23 | — | — | US | disclosed |
| EP-1207160-A1 | Process for the preparation of 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)-methyl)-4H-carbazol-4-one | Hanmi Pharm. Co., Ltd. (KR) | 2002-05-22 | — | — | EP | disclosed |
| US-6388091-B1 | IN PRESENCE OF A HALOSILANE COMPOUND; CRYSTALLIZATION, PURIFICATION | HANMI PHARM. CO., LTD. (KR) | 2002-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061919-A1 | PROCESS FOR THE PREPARATION OF 1,2,3,9-TETRAHYDRO-9-METHYL-3-{(2-METHYL-1H-IMIDAZOL-1-YL)METHYL}-4H-CARBAZOL-4-ONE | JAK1, CILK1, AZI2 | ALDH1A1 1316/4885HSD17B10 3060/4885HPGD 2271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.