Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474633 | 0.87 | MAPT (0.45) | MAPTCYP2C9CYP2C19 | |
| SCHEMBL7480389 | 0.87 | MEN1 (0.34) | MAPTTP53KMT2AMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7472629 | 0.86 | MAPT (0.44) | MAPTCYP2C9CYP2C19 | |
| SCHEMBL8299995 | 0.85 | MEN1 (0.34) | MAPTTP53KMT2AMEN1CYP1A2 | |
| SCHEMBL7484182 | 0.85 | MAPT (0.45) | MAPTMMP3TP53CYP2C9CYP2C19 | |
| SCHEMBL7474801 | 0.84 | MAPT (0.47) | MAPTTP53KMT2AMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7480495 | 0.84 | MAPT (0.46) | MAPTTP53KMT2AMEN1CYP1A2 | |
| SCHEMBL7471608 | 0.79 | KDM4E (0.39) | MAPTTP53 | |
| SCHEMBL8175563 | 0.78 | GNAI3 (0.38) | MAPTTP53 | |
| SCHEMBL7484144 | 0.77 | KDM4E (0.41) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |