Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474633 | 0.94 | MAPT (0.45) | MAPTCYP2C9KDM4EALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL7472629 | 0.93 | MAPT (0.44) | MAPTCYP2C9KDM4EALDH1A1CYP3A4 | |
| SCHEMBL7471608 | 0.89 | KDM4E (0.39) | MAPTKDM4ETP53 | |
| SCHEMBL7484144 | 0.87 | KDM4E (0.41) | MAPTKDM4EALDH1A1TP53 | |
| SCHEMBL7473775 | 0.85 | DNM1 (0.37) | TSHR | |
| SCHEMBL8175563 | 0.85 | GNAI3 (0.38) | MAPTKDM4ETP53 | |
| SCHEMBL7475727 | 0.85 | MAPT (0.42) | MAPTMMP3CYP2C9TP53CYP2C19 | |
| SCHEMBL7474801 | 0.84 | MAPT (0.47) | MAPTCYP2C9TP53CYP2C19 | |
| SCHEMBL7479745 | 0.84 | DPP4 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7480495 | 0.84 | MAPT (0.46) | MAPTCYP2C9TP53CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |