Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475148 | 0.81 | CHRNA7 (0.34) | BCHEALDH1A1PTGDR2 | |
| SCHEMBL7471855 | 0.74 | HDAC3 (0.39) | BCHESLC9A1ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL7482477 | 0.65 | L3MBTL1 (0.43) | SMYD3SMN1; SMN2 | |
| SCHEMBL10293063 | 0.64 | CYP2D6 (0.37) | ALDH1A1CYP1A2CYP2C19MAPTCYP2C9 | |
| SCHEMBL5758726 | 0.64 | F2RL3 (0.33) | ALDH1A1CYP2C9 | |
| SCHEMBL12327545 | 0.63 | BACE1 (0.34) | — | |
| SCHEMBL20589075 | 0.62 | POLB (0.49) | BCHEALDH1A1MAPTNPC1NFKB1 | |
| SCHEMBL7146974 | 0.61 | HTR1A (0.39) | — | |
| SCHEMBL6598647 | 0.61 | KDM1A (0.39) | — | |
| SCHEMBL20139542 | 0.61 | MGLL (0.51) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244623-A1 | A PROCESS FOR PREPARING 4-SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001046147-A1 | A PROCESS FOR PREPARING 4-SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |