Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 7/20 | 0.67 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.61 |
| ▸ | ABL1 | P00519 | 2/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | PRKCA | P17252 | 1/20 | 0.61 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.57 |
| ▸ | JAK2 | O60674 | 2/20 | 0.53 |
| ▸ | JAK3 | P52333 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | CDK4 | P11802 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
| ▸ | LYN | P07948 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470657 | 0.86 | IKBKB (0.67) | IKBKBCDK2CDK4NPC1MAPT | |
| SCHEMBL7470733 | 0.84 | PIK3CA (0.66) | IKBKBABL1CAMK2DCDK2CDK1 | |
| SCHEMBL1593016 | 0.82 | PRKCD (0.79) | IKBKBPRKCDABL1EGFRPRKCA | |
| SCHEMBL7469906 | 0.82 | IKBKB (0.63) | IKBKBPRKCDABL1EGFRPRKCA | |
| SCHEMBL7474268 | 0.82 | PIK3CA (0.65) | IKBKBCDK2CDK4CDK1NPC1 | |
| SCHEMBL4029958 | 0.81 | ABL1 (0.72) | IKBKBPRKCDABL1EGFRPRKCA | |
| SCHEMBL7466208 | 0.81 | PIK3CG (0.72) | IKBKBABL1EGFRPRKCACAMK2D | |
| SCHEMBL7464559 | 0.81 | IKBKB (0.53) | IKBKBABL1JAK2JAK3CDK2 | |
| SCHEMBL6980400 | 0.78 | CDK2 (0.69) | IKBKBPRKCDEGFRPRKCAJAK2 | |
| SCHEMBL5780207 | 0.78 | PRKCD (0.55) | IKBKBPRKCDABL1EGFRPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233461-B2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 2002-05-29 | — | — | EP | disclosed |