Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.72 |
| ▸ | PRKCA | P17252 | 3/20 | 0.72 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.72 |
| ▸ | EGFR | P00533 | 1/20 | 0.72 |
| ▸ | BCR | P11274 | 3/20 | 0.69 |
| ▸ | SRC | P12931 | 1/20 | 0.69 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.67 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.66 |
| ▸ | JAK2 | O60674 | 2/20 | 0.62 |
| ▸ | JAK3 | P52333 | 1/20 | 0.62 |
| ▸ | IKBKB | O14920 | 3/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.59 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.59 |
| ▸ | CDK2 | P24941 | 2/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.57 |
| ▸ | PRKCG | P05129 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472770 | 0.92 | ABL1 (0.67) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL1593016 | 0.91 | PRKCD (0.79) | ABL1PRKCAPRKCDEGFRBCR | |
| Nitric Acid SCHEMBL10765825 | 0.89 | ABL1 (0.68) | ABL1PRKCAPRKCDEGFRBCR | |
| Nitric Acid SCHEMBL10765821 | 0.89 | ABL1 (0.68) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL7470875 | 0.84 | PLK1 (0.63) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL7470313 | 0.84 | ABL1 (0.58) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL7467852 | 0.84 | PIK3CA (0.65) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL4903317 | 0.84 | ABL1 (0.70) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL6262145 | 0.84 | ABL1 (1.00) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL3521444 | 0.83 | CAMK2D (0.63) | ABL1PRKCAPRKCDEGFRBCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85103378-A | Process for preparing a group of novel compounds, formulations containing these compounds and their use in therapy | — | 1986-07-09 | — | — | CN | claimed |
| EP-0164204-A1 | Novel pharmaceutically useful pyrimidines | FISONS plc (GB) | 1985-12-11 | — | — | EP | claimed |
| WO-2013120852-A1 | INTERMEDIATES FOR A NOVEL PROCESS OF PREPARING IMATINIB AND RELATED TYROSINE KINASE INHIBITORS | GRINDEKS, A JOINT STOCK COMPANY (LV) | 2013-08-22 | — | — | WO | disclosed |
| US-8389442-B2 | N-phenyl-′(4-pyridyl)-azinyl!amine derivatives as plant protection agents | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |
| EP-1613156-B1 | N-PHENYL- \" (4-PYRIDYL)- AZINYL]AMINE DERIVATIVES AS PLANT PROTECTION AGENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-06 | — | — | EP | disclosed |
| CN-100374434-C | Microbiocidal N-Phenyl-N-[4-pyridyl-pyrimidin-2-yl]-amine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-12 | — | — | CN | disclosed |
| CN-100374434-C | Microbiocidal N-Phenyl-N-[4-pyridyl-pyrimidin-2-yl]-amine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-12 | — | — | CN | disclosed |
| US-7205301-B2 | Microbiocidal N-phenyl-n-[4-(4-pyridyl)-2-pyrimidin-2-yl]-amine derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-7205301-B2 | Microbiocidal N-phenyl-n-[4-(4-pyridyl)-2-pyrimidin-2-yl]-amine derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-20070032490-A1 | N-Phenyl-'(4-pyridyl)-azinyl!amine derivatives as plant protection agents | SYNGENTA CROP PROTECTION, INC. | 2007-02-08 | — | — | US | disclosed |
| EP-1471786-B1 | MICROBIOCIDAL N-PHENYL-N- 4-(4-PYRIDYL)-2-PYRIMIDIN-2-YL|-AMINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-12-27 | — | — | EP | disclosed |
| EP-0672041-B1 | PHARMACOLOGICALLY ACTIVE PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 2001-11-14 | — | — | EP | disclosed |
| US-5728708-A | ANTITUMOR AGENTS | NOVARTIS CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0233461-B1 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 1996-03-20 | — | — | EP | disclosed |
| EP-0672041-A1 | PHARMACOLOGICALLY ACTIVE PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Novartis AG (CH) | 1995-09-20 | — | — | EP | disclosed |
| WO-1995009853-A1 | PHARMACOLOGICALLY ACTIVE PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CIBA-GEIGY AG (CH) | 1995-04-13 | — | — | WO | disclosed |
| US-4876252-A | ADMINISTERING ANTIASTHMATIC OR ANTIALLERGEN | AMERICAN CYANAMID COMPANY (US) | 1989-10-24 | — | — | US | disclosed |
| US-4788195-A | TREATING ASTHMA, ALLERGIC DISEASES, INFLAMMATION AND DIABETES IN MAMMALS | AMERICAN CYANAMID COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0233461-A2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID COMPANY (US) | 1987-08-26 | — | — | EP | disclosed |
| EP-0164204-A1 | Novel pharmaceutically useful pyrimidines | FISONS plc (GB) | 1985-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032490-A1 | N-Phenyl-'(4-pyridyl)-azinyl!amine derivatives as plant protection agents | CYP1A1, NAT1, AKR7A2 | ABL1 717/4885PRKCA 2482/4885PRKCD 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.