Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475780 | 0.91 | AVPR2 (0.49) | AVPR2AVPR1APOLBCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7374740 | 0.78 | LMNA (0.42) | AVPR2AVPR1APOLBMEN1KMT2A | |
| SCHEMBL7751057 | 0.78 | AVPR2 (0.51) | AVPR2AVPR1APOLBMEN1KMT2A | |
| SCHEMBL7336797 | 0.77 | AVPR2 (0.50) | AVPR2AVPR1APOLBSMN1; SMN2MEN1 | |
| SCHEMBL8722760 | 0.75 | MAPT (0.67) | AVPR2AVPR1APOLBCYP1A2CYP3A4 | |
| SCHEMBL8901810 | 0.75 | MAPT (0.67) | AVPR2AVPR1APOLBCYP1A2CYP3A4 | |
| SCHEMBL7343269 | 0.74 | AVPR2 (0.41) | AVPR2AVPR1APOLBCYP1A2CYP3A4 | |
| SCHEMBL11600983 | 0.73 | MAPT (0.70) | POLBMEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL8902002 | 0.73 | KMT2A (0.58) | AVPR2AVPR1ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7337768 | 0.72 | AVPR2 (0.42) | AVPR2AVPR1APOLBCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |