SCHEMBL7475971

SCHEMBL7475971

N#CCC1CCC2(CC1)OCCO2

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13674327 0.80 GPR119 (0.33) CTSSCTSK
SCHEMBL30843415 0.79 LMNA (0.30)
SCHEMBL8516141 0.73 GPR119 (0.32)
SCHEMBL24093158 0.72
SCHEMBL442550 0.71 CYP3A4 (0.44)
SCHEMBL51112 0.71 GPR119 (0.34)
SCHEMBL963183 0.71
SCHEMBL87245 0.71 POLB (0.42)
SCHEMBL25346880 0.71 GPR119 (0.31)
SCHEMBL1968451 0.71 GPR119 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117658827-A Synthesis method of alkyl cyclohexylethylamine 上海睿智化学研究有限公司 2024-03-08 CN claimed
CN-117658827-A Synthesis method of alkyl cyclohexylethylamine 上海睿智化学研究有限公司 2024-03-08 CN disclosed
EP-0937708-B1 Sulphonamide derivatives LILLY CO ELI (US) 2002-12-18 EP disclosed
US-6362230-B1 ALZHEIMER'S DISEASE ELI LILLY AND COMPANY 2002-03-26 US disclosed
US-6174922-B1 FOR POTENTIATING GLUTAMATE RECEPTOR FUNCTION IN WARM BLOODED MAMMAL ELI LILLY AND COMPANY 2001-01-16 US disclosed
EP-0937708-A2 sulphonamide derivatives ELI LILLY AND COMPANY (US) 1999-08-25 EP disclosed
US-5034381-A Antagonist CIBA-GEIGY CORPORATION (US) 1991-07-23 US disclosed
EP-0323807-A2 Certain 2-substituted adenosine derivatives CIBA-GEIGY AG (CH) 1989-07-12 EP disclosed