SCHEMBL9350819

SCHEMBL9350819

CC(C#N)(CCC(=O)NC1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1)/N=N/C(C)(C#N)CCC(=O)NC1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.32
EPHX2 P34913 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9350824 1.00 GAA (0.37) GAAHPGDEPHX2MEN1KMT2A
SCHEMBL7476001 0.82 GAA (0.45) GAAHPGDEPHX2MEN1KMT2A
SCHEMBL13412664 0.78 NPSR1 (0.41) GAAHPGDEPHX2KMT2AALDH1A1
SCHEMBL9041095 0.78 ALDH1A1 (0.54) GAAHPGDEPHX2ALDH1A1SIGMAR1
SCHEMBL10441567 0.77
SCHEMBL10441568 0.77
SCHEMBL9381217 0.75 NPSR1 (0.38) GAAHPGDEPHX2KMT2AALDH1A1
SCHEMBL15355948 0.74 GAA (0.31) GAA
SCHEMBL7470309 0.72 ALDH1A1 (0.38) GAAHPGDEPHX2ALDH1A1
SCHEMBL9350745 0.70 EPHX2 (0.34) GAAHPGDEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389429-B1 Azo compounds containing hindered amine moieties with low basicity CIBA GEIGY AG (CH) 1994-09-21 EP claimed
US-5021480-A Azo free radical initiators containing hindered amine moieties with low basicity CIBA-GEIGY CORPORATION (US) 1991-06-04 US claimed
EP-0389429-B1 Azo compounds containing hindered amine moieties with low basicity CIBA GEIGY AG (CH) 1994-09-21 EP disclosed
US-5021480-A Azo free radical initiators containing hindered amine moieties with low basicity CIBA-GEIGY CORPORATION (US) 1991-06-04 US disclosed
EP-0389429-A2 Azo compounds containing hindered amine moieties with low basicity CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed