Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | DRD4 | P21917 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475139 | 0.88 | GRM2 (0.62) | MAPTLMNAGFERDRD4GAA | |
| SCHEMBL7473319 | 0.86 | GRM2 (0.51) | MAPTLMNAGFERDRD4GAA | |
| SCHEMBL7477760 | 0.83 | MAPT (0.56) | MAPTLMNAGFERDRD4GAA | |
| SCHEMBL7474510 | 0.82 | KDM4E (0.48) | MAPTLMNAGFERDRD4GAA | |
| SCHEMBL4146837 | 0.81 | LMNA (1.00) | MAPTLMNAGFERDRD4GAA | |
| SCHEMBL7477891 | 0.80 | GRM2 (0.49) | LMNADRD4GAAGRM2SMN1; SMN2 | |
| SCHEMBL7477813 | 0.80 | KDM4E (0.49) | MAPTLMNAGFERDRD4GAA | |
| SCHEMBL7474146 | 0.79 | HPGD (0.59) | MAPTLMNAGAAGRM2SMN1; SMN2 | |
| SCHEMBL7477326 | 0.79 | MEN1 (0.52) | MAPTLMNADRD4GAAGRM2 | |
| SCHEMBL7477902 | 0.78 | GRM2 (0.64) | DRD4GRM2SMN1; SMN2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-B1 | PROTON PUMP INHIBITOR | APOTEX INC (CA) | 2002-05-15 | — | — | EP | claimed |
| US-6093738-A | IMIDAZO(1,2-D)-THIADIAZOLE COMPOUNDS; PEPTIC ULCER TREATMENT | KARIMIAN KHASHAYAR (CA) | 2000-07-25 | — | — | US | claimed |
| EP-0883622-B1 | PROTON PUMP INHIBITOR | APOTEX INC (CA) | 2002-05-15 | — | — | EP | disclosed |