Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 8/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 3/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073174 | 0.79 | ADORA1 (0.37) | PIK3CAPIK3CBPIK3CGPIK3CDPI4KB | |
| Bromide SCHEMBL7480303 | 0.70 | ALDH1A1 (0.56) | PIK3CAPIK3CBPIK3CGPIK3CDCFTR | |
| SCHEMBL3536095 | 0.69 | TSHR (0.58) | KDM4EALDH1A1MAPT | |
| SCHEMBL13314772 | 0.69 | TSHR (0.54) | ADORA1ALDH1A1MAPT | |
| SCHEMBL13314773 | 0.68 | TSHR (0.56) | APOBEC3AAPOBEC3GALDH1A1MAPT | |
| SCHEMBL7478299 | 0.67 | ALDH1A1 (0.34) | PIK3CAPIK3CBPIK3CGPIK3CDPI4KB | |
| SCHEMBL3537945 | 0.65 | PDK1 (0.47) | APOBEC3AAPOBEC3GCFTRALDH1A1MAPT | |
| SCHEMBL3535533 | 0.65 | CHKA (0.41) | MAPT | |
| Hydrochloric Acid SCHEMBL3538938 | 0.64 | CHKA (0.40) | MAPT | |
| SCHEMBL7486311 | 0.64 | POLB (0.33) | PIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843681-B1 | HETEROCYCLE-FUSED THIAZOLE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO LTD (KR) | 2002-03-06 | — | — | EP | disclosed |