Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1052638 | 0.82 | LMNA (0.42) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL8073165 | 0.79 | KDM4E (0.33) | ALDH1A1RAB9APOLBKDM4EMEN1 | |
| SCHEMBL6067826 | 0.77 | NPC1 (0.41) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| Bromide SCHEMBL7480303 | 0.73 | ALDH1A1 (0.56) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL4597273 | 0.73 | ALDH1A1 (0.50) | ALDH1A1RAB9APOLBKDM4EMEN1 | |
| Bromide SCHEMBL6117488 | 0.72 | ALDH1A1 (0.49) | ALDH1A1RAB9APOLBKDM4EMEN1 | |
| Bromide SCHEMBL6118973 | 0.69 | KDM4E (0.35) | ALDH1A1RAB9APOLBKDM4EMEN1 | |
| SCHEMBL13853414 | 0.67 | NPC1 (0.43) | ALDH1A1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL7476595 | 0.67 | PIK3CA (0.40) | ALDH1A1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3540501 | 0.67 | RAB9A (0.67) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843681-B1 | HETEROCYCLE-FUSED THIAZOLE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO LTD (KR) | 2002-03-06 | — | — | EP | disclosed |