Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477008 | 0.84 | F2 (0.53) | NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL6753946 | 0.77 | NPC1 (0.81) | NPC1RAB9AMAPTPOLBGAA | |
| SCHEMBL6753967 | 0.77 | POLB (0.83) | NPC1RAB9AMAPTPOLBGAA | |
| SCHEMBL30583066 | 0.77 | RAB9A (1.00) | NPC1RAB9AMAPTPOLBALDH1A1 | |
| SCHEMBL784574 | 0.77 | RAB9A (1.00) | NPC1RAB9AMAPTPOLBALDH1A1 | |
| SCHEMBL5274918 | 0.76 | POLB (0.80) | NPC1RAB9AMAPTPOLBGAA | |
| SCHEMBL30583064 | 0.76 | POLB (0.80) | NPC1RAB9AMAPTPOLBGAA | |
| SCHEMBL6367344 | 0.76 | POLB (0.80) | NPC1RAB9AMAPTPOLBGAA | |
| SCHEMBL8974511 | 0.76 | POLB (0.80) | NPC1RAB9AMAPTPOLBGAA | |
| SCHEMBL8958097 | 0.76 | POLB (0.80) | NPC1RAB9AMAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026933-A1 | SUBSTITUTED AMIDINOARYL DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | claimed |