Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2707747 | 0.80 | PREP (0.46) | DPP4CHRNB2CHRNA7CHRNA4DRD2 | |
| SCHEMBL203889 | 0.80 | PREP (0.46) | DPP4CHRNB2CHRNA7CHRNA4DRD2 | |
| SCHEMBL749251 | 0.76 | KCNH2 (0.52) | — | |
| SCHEMBL14334765 | 0.75 | KCNH2 (0.41) | DPP4 | |
| SCHEMBL204560 | 0.74 | FPR3 (0.60) | CHRNB2CHRNA7CHRNA4DRD2CTSL | |
| SCHEMBL2706908 | 0.74 | FPR3 (0.60) | CHRNB2CHRNA7CHRNA4DRD2CTSL | |
| SCHEMBL748770 | 0.72 | CYP3A4 (0.59) | — | |
| SCHEMBL9980163 | 0.71 | CTSL (0.50) | CHRNB2CHRNA7CHRNA4DRD2CTSL | |
| SCHEMBL751023 | 0.70 | CYP3A4 (0.42) | — | |
| SCHEMBL14334764 | 0.69 | EGFR (0.40) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |