Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468349 | 0.94 | L3MBTL1 (0.54) | L3MBTL1HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL29025528 | 0.84 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL10690887 | 0.80 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL22966593 | 0.78 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7931376 | 0.78 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5804308 | 0.78 | L3MBTL1 (0.67) | L3MBTL1HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL7562125 | 0.78 | HDAC3 (0.71) | L3MBTL1HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL4172605 | 0.77 | L3MBTL1 (0.70) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16342957 | 0.77 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL19421299 | 0.76 | LTA4H (0.57) | L3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757986-B1 | Arylpiperidine and arylpiperazine derivatives and drugs containing the same | SUNTORY LTD (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-5723475-A | Arylpiperidine and arylpiperazine derivatives and medicament containing the same | SUNTORY LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0757986-A1 | ARYLPIPERIDINE AND ARYLPIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |