SCHEMBL10690887

SCHEMBL10690887

O=C(CO)Nc1ccccc1Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.64
ALDH1A1 P00352 5/20 0.61
HPGD P15428 3/20 0.61
MAOB P27338 1/20 0.48
LMNA P02545 2/20 0.48
HTT P42858 1/20 0.48
MAPT P10636 1/20 0.47
RECQL P46063 1/20 0.47
PKM P14618 1/20 0.47
KMT2A Q03164 1/20 0.45
ATM Q13315 1/20 0.45
POLB P06746 2/20 0.44
GAA P10253 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10691682 0.87 NPC1 (0.53) L3MBTL1ALDH1A1HPGDLMNAKMT2A
SCHEMBL10693682 0.87 L3MBTL1 (0.50) L3MBTL1ALDH1A1HPGDLMNAHTT
SCHEMBL29025528 0.85 L3MBTL1 (0.62) L3MBTL1ALDH1A1HPGDMAOBLMNA
SCHEMBL10690219 0.85 ALDH1A1 (0.59) L3MBTL1ALDH1A1HPGDLMNAHTT
SCHEMBL22966593 0.85 L3MBTL1 (0.62) L3MBTL1ALDH1A1HPGDMAOBLMNA
SCHEMBL5804308 0.85 L3MBTL1 (0.67) L3MBTL1ALDH1A1HPGDMAOBLMNA
SCHEMBL7931376 0.85 L3MBTL1 (0.62) L3MBTL1ALDH1A1HPGDMAOBLMNA
SCHEMBL4172605 0.84 L3MBTL1 (0.70) L3MBTL1ALDH1A1HPGDMAOBLMNA
SCHEMBL10690936 0.84 ALDH1A1 (0.56) L3MBTL1ALDH1A1LMNAMAPTPKM
SCHEMBL10693458 0.84 FPR1 (0.48) L3MBTL1ALDH1A1HPGDLMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0098743-B1 PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE Yu, Ruey J., Dr. (US) 1988-09-28 EP claimed