Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474730 | 0.85 | CYP2C19 (0.48) | HTR1ASLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL4317190 | 0.83 | PDE10A (0.38) | PDE10ABRPF1BRD4KITCHRNB4 | |
| SCHEMBL4312056 | 0.82 | MAPT (0.46) | PDE10AKITMAPK13MAPK12MAPK11 | |
| SCHEMBL4312809 | 0.82 | CYP2C19 (0.49) | HTR1ASLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL8651595 | 0.79 | PDE10A (0.45) | PDE10ABRPF1BRD4KITGHSR | |
| SCHEMBL7476039 | 0.77 | KDM4E (0.45) | HTR1ATDP1 | |
| SCHEMBL4329085 | 0.76 | MAPK13 (0.48) | KITMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7469509 | 0.74 | HTR2C (0.46) | HTR1ASLC6A2SLC6A4TDP1 | |
| SCHEMBL4317318 | 0.73 | HTR6 (0.45) | HTR1ASLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL4311425 | 0.72 | HTR1A (0.44) | HTR1ASLC6A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178973-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia AB (SE) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000076984-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2000-12-21 | — | — | WO | disclosed |