Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 14/20 | 0.82 |
| ▸ | PDE4A | P27815 | 12/20 | 0.82 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.82 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.82 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.66 |
| ▸ | PDE5A | O76074 | 1/20 | 0.59 |
| ▸ | PDE1A | P54750 | 1/20 | 0.59 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.59 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458162 | 0.88 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL7423009 | 0.86 | PDE4D (0.76) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL19075717 | 0.85 | PDE4A (0.74) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL19083721 | 0.85 | PDE4D (0.74) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL15595277 | 0.84 | KMT2A (0.68) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL28884189 | 0.83 | PDE4D (0.67) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL7423857 | 0.82 | PDE4D (0.82) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL4728938 | 0.82 | PDE4B (0.80) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9272637 | 0.81 | PDE4B (0.65) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL5309884 | 0.80 | PDE4D (0.67) | PDE4DPDE4APDE4BPDE4CPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998056756-A1 | CATECHOL AMINO ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEIL JEDANG CORPORATION (KR) | 1998-12-17 | — | — | WO | claimed |
| WO-1998056756-A1 | CATECHOL AMINO ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEIL JEDANG CORPORATION (KR) | 1998-12-17 | — | — | WO | disclosed |