Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 5/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 14/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475447 | 0.81 | GRIA1 (0.47) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7652792 | 0.78 | GRIA1 (0.52) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7469264 | 0.78 | GRIA1 (0.52) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7469005 | 0.78 | GRIA1 (0.52) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7469450 | 0.74 | GRIA1 (0.59) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7469496 | 0.73 | GRIA1 (0.44) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7474813 | 0.73 | GRIA2 (0.46) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7474858 | 0.72 | GRIA1 (0.44) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7474718 | 0.72 | GRIA4 (0.53) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7469696 | 0.71 | GRIA1 (0.34) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937708-B1 | Sulphonamide derivatives | LILLY CO ELI (US) | 2002-12-18 | — | — | EP | disclosed |
| US-6362230-B1 | ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6174922-B1 | FOR POTENTIATING GLUTAMATE RECEPTOR FUNCTION IN WARM BLOODED MAMMAL | ELI LILLY AND COMPANY | 2001-01-16 | — | — | US | disclosed |
| WO-1999043285-A2 | SULPHONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1999-09-02 | — | — | WO | disclosed |
| EP-0937708-A2 | sulphonamide derivatives | ELI LILLY AND COMPANY (US) | 1999-08-25 | — | — | EP | disclosed |