Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.64 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 3/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477463 | 0.87 | MRGPRX4 (0.52) | PTGDR2MRGPRX4PTGER1MAOBPPIA | |
| SCHEMBL31562849 | 0.83 | PTGDR2 (0.50) | PTGDR2MRGPRX4MAOBELANELTB4R | |
| Acetoacetic Acid SCHEMBL27720127 | 0.82 | KDM4E (0.51) | PTGDR2MRGPRX4PTGER1MAOBF2 | |
| SCHEMBL18528829 | 0.82 | PTGDR2 (0.60) | PTGDR2 | |
| SCHEMBL5089130 | 0.81 | MRGPRX4 (0.53) | PTGDR2MRGPRX4PTGER1MAOBELANE | |
| SCHEMBL1647357 | 0.81 | FOLH1 (0.62) | PTGDR2MRGPRX4PTGER1MAOBPPIA | |
| SCHEMBL8113906 | 0.81 | MRGPRX4 (0.50) | PTGDR2MRGPRX4PTGER1MAOBPTPN1 | |
| SCHEMBL6766128 | 0.80 | MAOB (0.57) | MRGPRX4MAOB | |
| SCHEMBL7909009 | 0.80 | PPARD (0.59) | MAOBELANELTB4RLTB4R2F2 | |
| SCHEMBL10419985 | 0.80 | PTGDR2 (0.62) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183235-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071510-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |