Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28134315 | 0.82 | ALDH1A1 (0.39) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL28890950 | 0.74 | ALDH1A1 (0.38) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL28728640 | 0.72 | MAPT (0.41) | KDM4EMAPK1MAPTKMT2AALDH1A1 | |
| SCHEMBL30825761 | 0.72 | MAPT (0.40) | KDM4ETP53MAPK1RAB9AMAPT | |
| SCHEMBL22410854 | 0.71 | MAPT (0.36) | TAAR1MAPTKMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL29143517 | 0.69 | MAPT (0.36) | MAPK1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL9139763 | 0.67 | ATM (0.41) | MAPK1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL1137916 | 0.67 | MAPT (0.40) | KDM4EMAPK1MAPTKMT2AALDH1A1 | |
| SCHEMBL3520478 | 0.67 | ATM (0.38) | MAPK1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL6866868 | 0.67 | MAPT (0.43) | KDM4ETP53MAPK1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923551-B1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PROD (US) | 2002-06-05 | — | — | EP | disclosed |