Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27619771 | 0.88 | MAOB (0.41) | PTGS2MAOBSMN1; SMN2NPC1PKM | |
| SCHEMBL23053214 | 0.79 | LMNA (0.45) | MAOBSMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL3904573 | 0.78 | LMNA (0.46) | MAOBSMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL5243540 | 0.78 | MAOB (0.40) | MAOBSMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL17599975 | 0.76 | TRIM24 (0.40) | MAOBTSHRMEN1KMT2ATRIM24 | |
| SCHEMBL2325762 | 0.76 | — | — | |
| SCHEMBL732708 | 0.75 | — | — | |
| SCHEMBL7379152 | 0.75 | MAOB (0.41) | MAOBSMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL14292421 | 0.73 | ACACB (0.42) | MAOBSMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL28996324 | 0.72 | MEN1 (0.41) | MAOBSMN1; SMN2NPC1PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661688-B | Synthetic method of non-steroidal anti-inflammatory drug tolmetin | 杭州迪克科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-112661688-A | Synthetic method of non-steroidal anti-inflammatory drug tolmetin | 杭州迪克科技有限公司 | 2021-04-16 | — | — | CN | disclosed |
| EP-0800390-B1 | CYCLOPROPYLPYRROLOINDOLE-OLIGOPEPTIDE ANTICANCER AGENTS | UNIV ALBERTA (CA) | 2002-12-04 | — | — | EP | disclosed |
| EP-0800390-A4 | CYCLOPROPYLPYRROLOINDOLE-OLIGOPEPTIDE ANTICANCER AGENTS | SYNPHAR LAB INC (CA) | 1999-01-20 | — | — | EP | disclosed |
| EP-0800390-A1 | CYCLOPROPYLPYRROLOINDOLE-OLIGOPEPTIDE ANTICANCER AGENTS | SYNPHAR LABORATORIES INC. (CA) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996023497-A1 | CYCLOPROPYLPYRROLOINDOLE-OLIGOPEPTIDE ANTICANCER AGENTS | SYNPHAR LABORATORIES, INC. (CA) | 1996-08-08 | — | — | WO | disclosed |
| US-5502068-A | ABILITY TO ALKYLATE DNA SEQUENCES | SYNPHAR LABORATORIES, INC. (CA) | 1996-03-26 | — | — | US | disclosed |