Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.39 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.39 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28996324 | 0.86 | MEN1 (0.41) | MAOBKDM4EMEN1MAPTHPGD | |
| SCHEMBL7376958 | 0.83 | KMT2A (0.40) | MAOBMEN1MAPTKMT2AELOVL1 | |
| SCHEMBL12469514 | 0.76 | MAOB (0.44) | MAOBMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7477619 | 0.75 | PTGS2 (0.45) | MAOBKDM4EMEN1MAPTHPGD | |
| SCHEMBL23053214 | 0.75 | LMNA (0.45) | MAOBKDM4EKMT2ALMNARAB9A | |
| SCHEMBL10095111 | 0.74 | MAOB (0.43) | MAOBMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL13881104 | 0.74 | MAOB (0.43) | MAOBMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL5243540 | 0.73 | MAOB (0.40) | MAOBMEN1KMT2ARAB9ANPC1 | |
| Water SCHEMBL28190269 | 0.72 | MAOB (0.42) | MAOBKDM4EMEN1MAPTKMT2A | |
| SCHEMBL7385357 | 0.72 | PTGS2 (0.42) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661688-B | Synthetic method of non-steroidal anti-inflammatory drug tolmetin | 杭州迪克科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-112661688-A | Synthetic method of non-steroidal anti-inflammatory drug tolmetin | 杭州迪克科技有限公司 | 2021-04-16 | — | — | CN | disclosed |
| US-5314910-A | 2-Heteroaromatic alkanoate esters useful as inhibitors of human leukocyte or neutrophil elastase | CORTECH INC. (US) | 1994-05-24 | — | — | US | disclosed |
| US-5240956-A | Phenyl 2-heteroaromatic-alkanoates, elastase inhibitors | CORTECH, INC. (US) | 1993-08-31 | — | — | US | disclosed |
| CN-1061152-A | ESTER INHIBITORS | CORTECH INC (US) | 1992-05-20 | — | — | CN | disclosed |
| EP-0484949-A2 | Ester inhibitors | CORTECH, INC. (US) | 1992-05-13 | — | — | EP | disclosed |
| US-4136097-A | COPPER(II) COMPLEX AS PROMOTER | MCNEIL LABORATORIES, INC. (US) | 1979-01-23 | — | — | US | disclosed |