Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CCR4 | P51679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468210 | 0.77 | CCR4 (0.36) | CCR4 | |
| SCHEMBL7466999 | 0.76 | AURKA (0.32) | CCR4 | |
| SCHEMBL7465352 | 0.74 | EPAS1 (0.40) | KDM4EMAPT | |
| SCHEMBL7470542 | 0.70 | GRIN1 (0.39) | — | |
| SCHEMBL8488354 | 0.69 | GRIN1 (0.40) | — | |
| SCHEMBL7471473 | 0.66 | GRIN1 (0.34) | KDM4EMAPT | |
| SCHEMBL7464603 | 0.66 | GRIN1 (0.39) | — | |
| SCHEMBL8487280 | 0.66 | GRIN1 (0.35) | — | |
| SCHEMBL8487286 | 0.66 | GRIN1 (0.35) | — | |
| SCHEMBL8930635 | 0.65 | GRIN1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783495-B1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER LTD (GB) | 2002-02-27 | — | — | EP | disclosed |
| US-5852016-A | Quinoxaline derivatives useful in therapy | PFIZER INC. (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0783495-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | Pfizer Limited (GB) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996009295-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER LIMITED (GB) | 1996-03-28 | — | — | WO | disclosed |