Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6193368 | 0.75 | CA12 (0.34) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL15012527 | 0.74 | GABRA1 (0.33) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL1615450 | 0.74 | ELANE (0.33) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL4727437 | 0.73 | — | — | |
| SCHEMBL30275444 | 0.69 | ALDH1A1 (0.34) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL30356675 | 0.68 | TP53 (0.32) | — | |
| SCHEMBL30136988 | 0.67 | TP53 (0.31) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL7646844 | 0.67 | ADORA2B (0.32) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL15012524 | 0.66 | CYP2C9 (0.31) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL10815505 | 0.64 | CA12 (0.35) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923561-B1 | HETEROCYCLIC METALLOPROTEASE INHIBITORS | PROCTER & GAMBLE (US) | 2002-10-23 | — | — | EP | disclosed |
| US-6399598-B1 | ORAL DISEASES; RHEUMATIC DISEASES; OSTEOPOROSIS | THE PROCTER & GAMBLE COMPANY | 2002-06-04 | — | — | US | disclosed |
| US-6121258-A | FOR TREATMENT OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS, SKIN DISORDERS, OCULAR DISORDERS, INFLAMMATION, GUM DISEASE | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| CN-1228772-A | Heterocyclic metalloprotease inhibitors | PROCTER & GAMBLE (US) | 1999-09-15 | — | — | CN | disclosed |