Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MPI | P34949 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068428 | 0.72 | KDM4E (0.42) | KDM4EALDH1A1MAPTMPINPC1 | |
| SCHEMBL7476386 | 0.72 | RAB9A (0.54) | KDM4EALDH1A1MAPTMPINPC1 | |
| Bromide SCHEMBL7483434 | 0.68 | SMN1; SMN2 (0.44) | KDM4EALDH1A1MAPTMPINPC1 | |
| Bromide SCHEMBL7483044 | 0.65 | TNKS2 (0.35) | KDM4EALDH1A1POLBHPGDMAPK1 | |
| SCHEMBL11574587 | 0.64 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTNPC1TP53 | |
| SCHEMBL23042072 | 0.58 | ADORA1 (0.58) | KDM4EALDH1A1MAPTMPINPC1 | |
| SCHEMBL2762670 | 0.58 | ADORA1 (0.58) | KDM4EALDH1A1MAPTMPINPC1 | |
| SCHEMBL2563054 | 0.57 | KDM4E (0.69) | KDM4EALDH1A1MAPTMPINPC1 | |
| SCHEMBL30953833 | 0.56 | ADORA1 (0.97) | KDM4EALDH1A1MAPTMPINPC1 | |
| SCHEMBL1745165 | 0.56 | ADORA1 (0.97) | KDM4EALDH1A1MAPTMPINPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843681-B1 | HETEROCYCLE-FUSED THIAZOLE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO LTD (KR) | 2002-03-06 | — | — | EP | disclosed |