Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 12/20 | 0.47 |
| ▸ | THRA | P10827 | 4/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005262 | 0.87 | THRB (0.43) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL7474453 | 0.85 | THRB (0.46) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL8347711 | 0.84 | THRB (0.52) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL7472949 | 0.82 | MEN1 (0.51) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL8006662 | 0.80 | THRB (0.44) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL7829095 | 0.80 | MEN1 (0.58) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL7999085 | 0.79 | THRB (0.53) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL7989856 | 0.79 | THRB (0.46) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL7477395 | 0.78 | THRB (0.53) | THRBTHRAP2RX7MEN1NR1I2 | |
| SCHEMBL7475466 | 0.78 | THRB (0.52) | THRBTHRAP2RX7MEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831088-B1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA SCHERING PLOUGH ANIMAL (JP) | 2002-11-27 | — | — | EP | claimed |
| US-5985875-A | USEFUL AS ANTI-PROTOZOAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-16 | — | — | US | claimed |
| EP-0831088-A1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-25 | — | — | EP | claimed |
| EP-0831088-B1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA SCHERING PLOUGH ANIMAL (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-5985875-A | USEFUL AS ANTI-PROTOZOAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0831088-A1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-25 | — | — | EP | disclosed |